The chart, and all rankings dated Nov. 16, will refresh on Billboard.com Tuesday, Nov. 12.
"Crave," which marks Lee's first No. 1 on the ranking, was remixed for clubs by Tracy Young, Benny Benassi and DJLW, among a host of others.
With 49 toppers on Dance Club Songs, which measures reports submitted by a national sample of club DJs and which launched as a national survey in the Billboard issue dated Aug. 28, 1976, Madonna outpaces runner-up Rihanna (33 No. 1s), while Beyoncé and Janet Jackson follow with 22 and 20, respectively.
"Crave" is Madonna's third leader, all this year, from her album Madame X, following "Medellín," with Maluma (June 29), and "I Rise" (Aug. 31). Madonna adds her ninth No. 1 this decade and has earned three each from her last three studio albums, with each triple tallied in a single year. Madonna also scored three No. 1s each from 2015's Rebel Heart ("Living for Love," "Ghosttown" and "B**** I'm Madonna," featuring Nicki Minaj) and 2012's MDNA ("Give Me All Your Luvin'," featuring Nicki Minaj and M.I.A., "Girl Gone Wild" and "Turn Up the Radio").
"Crave" additionally marks Madonna's ninth consecutive Dance Club Songs No. 1, her longest such streak. (Katy Perry holds the record with 18 straight No. 1s in 2009-17.) Twice before, Madonna managed seven straight No. 1s, first with "Causing a Commotion," from the Who's That Girl soundtrack (1987), through "Justify My Love," from her first greatest hits set, The Immaculate Collection (1991), and then with Ray of Light's "Nothing Really Matters" (1999) through Music's "Impressive Instant" (2001). Madonna's current run began with "Luvin' " in 2012.