According to the New England Genealogical Society, the funny lady and the Duchess of Cambridge are 15th cousins as they are each direct descendants of Edward III of England.
DeGeneres is also the 19th cousin, twice removed, of Queen Elizabeth II.
According to the website, Ancestry, US pop queen Madonna, Canadian singer Celine Dion and Camilla, Duchess of Cornwall, are all descended from the same French carpenter.
Records spanning more than 300 years from 1621 were published on the family and social history website Ancestry and revealed the unlikely link between the three women.
Camilla, the second wife of Prince Charles, Britain's heir to the throne - Madonna and Dion are all descended from French carpenter Zacharie Cloutier, according to the website.
'The fact that Camilla and Madonna are related, however distantly, highlights the truly unpredictable and entertaining nature of family history research,' said ancestry spokesperson Simon Harper.
However, Prince Charles has blasted this report in a bashful letter addressed to both Madonna and Celine Dion.
The explosive letter, published in 'The Prince Charles Letters' in 2011 informs to two pop queens that this information is 'so bally tenuous as to be barely worth mentioning'.
The Prince adds: 'Some might say I should ignore this sort of thing.'
However, Charles states in the letter that he is 'convinced that it’s all part of a ‘drip, drip, drip’ process that threatens to erode the monarchy'.
The letter, published on April 20, 2008, suggests that the website Ancestry are 'bent on mischief-making against the Royal Family'.
To end this, Charles drafted an open letter to the media detailing this this revelation is 'nonsense'.
Finally, Charles informed Madonna and Celine Dion that he would assume their approval of him 'scotching' the report should they choose not to reply to his letter.
In the letter he drafted for them to approve as words of their own, he included the line: 'We're not Royalty and we never will be.'