The star's latest release 'Living For Love' was made available in the UK earlier today (February 25), and has quickly scaled the iTunes sales chart.
It is only currently behind Noel Gallagher's promotional track 'Lock All The Doors', which has been released to promote his new album Chasing Yesterday.
'Living For Love's high sales have been achieved despite Radio 1 refusing to playlist the track as they deemed it irrelevant for their younger demographic - a decision which was protested by Madonna's fans.
'Living For Love' has been released in the UK today ahead of Madonna's performance at the Brit Awards this evening.
The star will take to the stage at London's O2 arena for the ceremony, which will be broadcast live on ITV from 8pm.
From Digital Spy